Dr. Niles Crane
Frasier character
Dr niles crane.jpg
David Hyde Pierce as Dr. Niles Crane
First appearance"The Good Son"
(episode 1.01)
Last appearance"Goodnight, Seattle (Part 2)"
(episode 11.24)
Portrayed byDavid Hyde Pierce
In-universe information
  • Martin Crane
  • Hester Crane
    (mother; deceased)
  • Frasier Crane
    (older brother)
  • Veronica "Ronee" Lawrence
  • Frederick Crane
  • Maris Crane
    (m. 1986; div. 1999)
  • Melinda "Mel" Karnofsky
    (m. 2000; div. 2000)
  • Daphne Moon
    (m. 2002)
ChildrenDavid Crane
(b. 2004; son, with Daphne)

Niles Crane (born 1957) is a fictional character on the American sitcom Frasier, a spin-off of the television show Cheers. He was portrayed by David Hyde Pierce. Niles is the younger brother of Frasier Crane (played by Kelsey Grammer).

Pierce was hired because Frasier producers saw his headshot and commented on how much he looked like a young Grammer. Unlike Frasier, part of whose background comes from Cheers, Niles' background is established over the course of Frasier.

Pierce has said that his character was originally explained to him as ''what Frasier would be if he had never gone to Boston and never been exposed to the people at Cheers.''

It has been suggested that "the difference between the brothers is that Frasier knows they're being pretentious; Niles honestly doesn't".